Nephrology Point of Care

Nephrology Point Of Care

Biophysics: an integrative approach for traditional therapy

Antonio Gorini
Department of Nephrology and Integrative Medicine, Biofisimed Ltd., Rome – Italy

Accepted: April 15, 2016
Published online: May 11, 2016
Corresponding author: Antonio Gorini, MD
Biofisimed Ltd.
Via Archimede, 138 – 00197 Rome, Italy

Traditionally, in the field of biology and physiology, humans are described mainly from a biochemical point of view, paying close attention to the metabolism as leading to the formation and destruction of the constituent molecules of the organism (enzymes, adenosine triphosphate [ATP], glycogen etc.). More recently the field has begun to understand that many of the physiological processes studied until now do not account for some of the functions of the living system. In particular the processes of biochemistry do not explain the quickness of biological
responses (muscular, enzymatic, hormonal, etc.) or of intercellular signaling.
By 1938 Prof. Albert Szent-Györgyi discovered the presence of actin and myosin in the muscular cells and has described the contraction mechanism: the energy provided from ATP (adenosine-triphosphate) leads to contraction of the fibers through the complex protein acto-myosin.
Prof. Szent-Györgyi received the Nobel Prize in Medicine in the 1937 for research on vitamin C and cellular respiration. He described several items of the process that now we call Krebs cycle 1.
In 1988 Szent-Györgyi pointed out that the classic mechanism of the neuromuscular junction does not explain the rate at which certain reactions occur (e.g., the closing of the eye at the time of perception of a foreign body on the eyelashes). This reflex motor action is too fast: there would not be time to put in place all of the molecular and chemical reactions required of the neuromuscular junction.
Szent-Györgyi’s work led him to describe the living system as an open system in which communication was carried out through biophysical information (photons, solitons, phonons etc.). Biophysical information moving at the speed of sound or light could explain the velocity of the physiological processes 2.
In biology, the life of the cell depends on the energy provided by ATP. In 1973, Davydoff described the process through which the energy obtained by ATP hydrolysis goes through the alpha helices of the proteins as a particular wave form called soliton. The soliton is a particular wave used to transfer energy in the living system. It is capable of transferring large amounts of energy at a constant speed and without dissipation 3.
There is a different electric potential between the internal and external sides of the cell membrane (-70 mV). When the cell is inflamed or diseased, mitochondria reduce their energy production, and the membrane potential decreases (e.g., -20 mV in cancer cells). The cell is, therefore, like a condenser with more negative charge inside and more positive charge outside. And every molecule has a specific electromagnetic signal. All molecules in living systems emit vibrations, solitons and photons to transfer energy and information. The human system continuously emits several electromagnetic signals. For this reason we can measure the electromagnetic field of the cells. And, as we know, in clinical practice, we use a lot of biophysical devices to detect electric, thermic, nuclear and magnetic cell activities (electrocardiography, nuclear magnetic resonance, thermography, etc.).
Pathological states, therefore, can be caused not only by organ disorders but also by defects in the biophysical processes, causing a reduction of energy states to levels far from thermodynamic equilibrium and coherence. The coherence concept was described by Frohlich in the 1988. He explained that all molecular systems produce giant coherent oscillations, which propagate in the body 4, 5. The coherent oscillations allow information to be transferred to the entire living system. The optimal synchronization of a multitude of processes on every level of the organism, as well as synchronization among these levels, is essential for the body’s health.
A pilot study by Foletti et al, published in this issue, considers the application of these concepts in chronic kidney disease (CKD). Biophysical therapy in particular has been used to prevent the progression of CKD in older patients. This could be one of many fields of application for biophysical therapies, allowing the recording of endogenous patterns of signals from the patient or their biological samples and turning them back on the patient to trigger a self-regulation response through a resonance effect 6. Resonance is the term used in physics to describe the strong coupling of systems having the same natural frequency (e.g., 2 tuning forks having the same frequency resonate even if we strike only 1 of the 2, causing the second to vibrate at a certain distance from the other) 2.
Nonionizing electromagnetic frequencies of low and very low intensity are able to induce functional changes in cells and biological tissues through a series of induced molecular interactions. Such electromagnetic waves do not modify the biological tissue or have any effect in ionizing it; the only thing it can do is to transfer information. By sequencing a limited set of informational codes – because each one induces a specific biological function – pathological tissue can be induced to restore its physiological homeostasis. Therefore, depending on the electromagnetic signal applied, it is able to reach the different kinds of tissue, reconstituting the proper functioning of the cells 6, 7.
As a confirmation of this, it has recently been discovered that DNA has the ability to issue electromagnetic waves at low frequency, and through them to transfer information to water and then to immune cells; therefore, DNA is able to receive internal and external signals and transfer information to the entire cell 8.
Biophysics applied to medicine is a very interesting field for many therapeutic areas and will be the field with the greatest developments in third-millennium medicine.


  • Financial support: No grants or funding have been received for this editorial.
  • Conflict of interest: None.


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